ARK Invest Biotech Active

ARK Genomic Revolution ETF

The ARK Genomic Revolution ETF’s (“Fund”) investment objective is long-term growth of capital.

$36.40

Key Metrics

TER 75.00% per year
Distribution policy Accumulating
Fund size USD 1,273 M
Inception date October 31, 2014
Holdings 35
Fund currency USD
Fund domicile US
Provider ARK
For full official fund details, factsheets, and holdings, visit ark-funds.com (opens in new tab).

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Historical Return

Last updated: Jun 15, 2026
1 Year +39.9%
3 Years (avg.) -1.7%
5 Years (avg.) -17.1%

Risk & Analysis Metrics

Last updated: Jun 15, 2026

Volatility

39.70% 1 Year
41.79% 3 Years
44.96% 5 Years
40.89% 10 Years

Max Drawdown

-27.51% 1 Year
-51.96% 3 Years
-80.30% 5 Years
-83.69% 10 Years

Sharpe Ratio

0.85 1 Year
0.07 3 Years
-0.28 5 Years
0.26 10 Years

Return Triangle (Heatmap)

Last updated: Jun 15, 2026
2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025
2014 5.6% 2.0% -4.4% 5.6% 3.3% 8.3% 24.0% 14.5% 3.1% 4.6% 1.1% 2.5%
2015 -1.6% -9.0% 5.6% 2.7% 8.8% 27.3% 15.9% 2.8% 4.5% 0.7% 2.2%
2016 -15.9% 9.5% 4.2% 11.5% 34.1% 19.0% 3.5% 5.3% 0.9% 2.6%
2017 42.5% 16.0% 22.6% 50.6% 27.6% 7.1% 8.7% 3.3% 4.8%
2018 -5.5% 13.7% 53.5% 24.2% 1.2% 3.9% -1.4% 0.9%
2019 36.7% 95.5% 36.0% 2.9% 5.9% -0.7% 1.8%
2020 179.6% 35.6% -6.4% -0.6% -6.8% -3.0%
2021 -34.2% -45.8% -29.6% -29.2% -21.5%
2022 -55.4% -27.2% -27.5% -18.0%
2023 18.8% -7.5% 0.4%
2024 -28.0% -7.7%
2025 18.4%

Distributions

*by ETF Portfolio Weight Last updated: Jun 15, 2026

Profit Margin Distribution

< 0%
85%
1y 3y N/A N/A
0 - 5%
0%
1y 3y N/A N/A
5 - 10%
0%
1y 3y N/A N/A
10 - 15%
0%
1y 3y N/A N/A
15 - 20%
8%
1y 3y N/A N/A
20 - 30%
2%
1y 3y N/A N/A
30 - 40%
1%
1y 3y N/A N/A
> 40%
3%
1y 3y N/A N/A

P/E Ratio Distribution

< 0
89%
1y 3y N/A N/A
0 - 10
0%
1y 3y N/A N/A
10 - 15
0%
1y 3y N/A N/A
15 - 20
1%
1y 3y N/A N/A
20 - 25
1%
1y 3y N/A N/A
25 - 35
6%
1y 3y N/A N/A
35 - 50
3%
1y 3y N/A N/A
> 50
0%
1y 3y N/A N/A

Discounted Cash Flow

Weighted Average Undervaluation
N/A
Undervalued
> 60%
0%
1y 3y N/A N/A
45 - 60%
0%
1y 3y N/A N/A
30 - 45%
0%
1y 3y N/A N/A
15 - 30%
0%
1y 3y N/A N/A
Fair (&plusmn;15%)
0%
1y 3y N/A N/A
Overvalued
15 - 30%
0%
1y 3y N/A N/A
30 - 45%
0%
1y 3y N/A N/A
45 - 60%
0%
1y 3y N/A N/A
> 60%
0%
1y 3y N/A N/A

Market Cap Size Distribution

Micro Cap
2.5%
1y 3y N/A N/A
Small Cap
33.7%
1y 3y N/A N/A
Mid Cap
40.8%
1y 3y N/A N/A
Large Cap
23.0%
1y 3y N/A N/A
Mega Cap
0.0%
1y 3y N/A N/A
Micro: < $300M Small: $300M–$2B Mid: $2B–$10B Large: $10B–$200B Mega: > $200B

Portfolio Concentration

*by ETF Portfolio Weight Last updated: Jun 15, 2026
35.7% Top 5 Holdings
58.6% Top 10 Holdings
100.0% Top 50 Holdings
100.0% Top 100 Holdings
Top 5 Companies
TEM Tempus AI Inc.
8.3%
CRSP CRISPR Therapeutics AG
8.0%
TWST Twist Bioscience Corp
7.2%
PSNL Personalis Inc
6.2%
GH Guardant Health Inc
6.0%

Latest News

about 1 year ago • accessnewswire.com

Levi & Korsinsky Investigates Tempus AI, Inc. (TEM) Over Potential Securities Fraud Allegations

NEW YORK, NY / ACCESS Newswire / May 30, 2025 / Levi & Korsinsky notifies investors that it has commenced an investigation of Tempus AI, Inc. ("Tem...

about 1 year ago • globenewswire.com

INVESTIGATION ALERT: Edelson Lechtzin LLP Announces Investigation Of Tempus AI Inc. (NASDAQ: TEM) and Encourages Investors with Substantial Losses or Witnesses with Relevant Information to Contact the Firm

NEWTOWN, Pa., May 30, 2025 (GLOBE NEWSWIRE) -- Edelson Lechtzin LLP is investigating potential violations of the federal securities laws involving ...

about 1 year ago • prnewswire.com

Rosen Law Firm Encourages Tempus AI, Inc. Investors to Inquire About Securities Class Action Investigation - TEM

NEW YORK , May 30, 2025 /PRNewswire/ -- Why: Rosen Law Firm, a global investor rights law firm, announces an investigation of potential securities ...

Average metrics of all companies in portfolio

Last updated: Jun 21, 2026
Market
Average
Market Cap The market value of the company. It's calculated by multiplying the share price by the number of outstanding shares. $10.2B -
Dividend Yield Yearly payout to shareholders per share. The percentage indicates the payout in relation to the share price. 0.03% 2.03%
Beta Indicates the relationship between the price performance of a share and the market. 1.95 -
P/E Ratio Ratio between share price and earnings per share. A low ratio could indicate that the stock is undervalued or investors aren't expecting high growth. A high ratio could indicate that the stock is overvalued or investors are expecting high growth. 30.96 28.29
Negative P/E Ratio a negative P/E ratio shows that the company is not profitable, and it shows how many years it would take the company to lose its entire market capitalisation if it did not change anything -42.66 -
Profitable Companies 11% -
PEG The ratio between the P/E ratio and the growth rate of the company's earnings per share in the last twelve months. A lower PEG could mean that a stock is undervalued. 17.96 14.56
Price to Sales Ratio Market cap divided by the revenue in the most recent year. 10.17 8.28
Price to Book Ratio Price to Book Ratio is the Market cap divided by the Book value of the company 4.04 10.72
Market
Average
Enterprise Value to EBIT Enterprise Value divided by EBIT -30.72 21.15
Enterprise Value to Revenue Enterprise value divided by revenue 10.88 8.72
Total Debt to Enterprise Value Total debt divided by enterprise value 0.12 0.05
Debt to Equity A higher ratio indicates a higher risk. However, the ratio is difficult to compare between industries where common amounts of debt vary. 0.03 0.33
Profit Margin Net income divided by revenue of the last 4 quarters. It indicates the company's profitability. -20.07% -6.18%
Quarterly Earnings Growth (YoY) The rate at which the company's net income has increased to the same quarter one year ago. +10.4% -117.9%
Return on Equity Equity divided by market cap. -13.30% 1.23%
Return on Assets Indicates a company's profitability in relation to its total assets. -16.84% 3.29%
Return on Invested Capital Return on invested capital (ROIC) is net income after dividends divided by the sum of debt and equity. It shows how effective a company is at turning capital invested by shareholders and other debtholders into profits. -20.45% 3.31%

Sectors

Manufacturing 46.4%
Professional, Scientific, and Technical Services 23.6%
Health Care and Social Assistance 17.1%
Healthcare 1.9%
Real Estate and Rental and Leasing 0.7%
Other 10.2%

Countries

United States 85.6%
Switzerland 7.5%
Other 3.2%
United Kingdom 2.9%
Germany 0.8%
Other 0.0%

Stock Screener

Select filters to narrow down the 34 investments below

34 companies

Limit holdings to companies in a single sector.

$0B >$1T

Ratio between share price and earnings per share. A low ratio could indicate undervaluation.

<0 >50

Ratio of dividends in the last 12 months to current share price.

0% 3%

Revenue increase compared to the same quarter one year ago.

0% 30%

Net income increase compared to the same quarter one year ago.

0% 30%

Profitability of the last quarter.

<-30% >30%

A higher ratio indicates a higher risk. The ratio is difficult to compare between industries.

<0 >3

Discounted cash flow valuation vs. current price. Positive = undervalued, negative = overvalued.

<-50% >+100%
Market Cap $8.87B
P/E Ratio -30.0
Dividends 0.0%
Total Investment $105.01M
Weight 8.25%

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Market Cap $5.22B
P/E Ratio -8.7
Dividends 0.0%
Total Investment $101.65M
Weight 7.99%

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Market Cap $936M
P/E Ratio -11.5
Dividends 0.0%
Total Investment $78.04M
Weight 6.13%

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Market Cap $17.47B
P/E Ratio -38.9
Dividends 0.0%
Total Investment $76.12M
Weight 5.98%

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Market Cap $3.51B
P/E Ratio -53.3
Dividends 0.0%
Total Investment $61.03M
Weight 4.79%

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Market Cap $24.5B
P/E Ratio 29.0
Dividends 0.0%
Total Investment $57.56M
Weight 4.52%

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Market Cap $33.14B
P/E Ratio -144.7
Dividends 0.0%
Total Investment $54.67M
Weight 4.30%

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Market Cap $1.35B
P/E Ratio -165.6
Dividends 0.0%
Total Investment $43.7M
Weight 3.43%

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Market Cap $4.28B
P/E Ratio 48.5
Dividends 0.0%
Total Investment $41.79M
Weight 3.28%

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Market Cap $2.81B
P/E Ratio -53.5
Dividends 0.0%
Total Investment $39.76M
Weight 3.12%

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Market Cap $1.76B
P/E Ratio -4.7
Dividends 0.0%
Total Investment $39.39M
Weight 3.09%

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Market Cap $12.25B
P/E Ratio -37.4
Dividends 0.0%
Total Investment $33.25M
Weight 2.61%

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Market Cap $1.18B
P/E Ratio -11.3
Dividends 0.0%
Total Investment $29.6M
Weight 2.33%

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Market Cap $1.52B
P/E Ratio -6.5
Dividends 0.0%
Total Investment $26.3M
Weight 2.07%

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Market Cap $434.84M
P/E Ratio -3.3
Dividends 0.0%
Total Investment $25.18M
Weight 1.98%

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