Luca Issi Score: 36
Analyst at
RBC Capital
Avg Return (Buy)
How much profit would you make?
Calculates the average return of all BUY recommendations after exactly 1 year (or today if newer).
Note: Sell ratings are ignored here to focus on investment potential.
Calculates the average return of all BUY recommendations after exactly 1 year (or today if newer).
Note: Sell ratings are ignored here to focus on investment potential.
+3.1%
1 Year Cap
Win Rate
How often is the direction correct?
Percentage of trades that are currently profitable.
• Buy: Stock price went UP 📈
• Sell: Stock price went DOWN 📉
Percentage of trades that are currently profitable.
• Buy: Stock price went UP 📈
• Sell: Stock price went DOWN 📉
50%
18 W / 18 L
Target Met
How often was the target reached?
Hits vs. Total.
Hits vs. Total.
64%
18 W / 10 L
Precision Hit
How often precise (±3%)?
Hits vs. Total.
Hits vs. Total.
18%
5 W / 23 L
Bullseye Hit
How often perfect (±1%)?
Hits vs. Total.
Hits vs. Total.
11%
3 W / 25 L
High Conviction
The "Brave" Trades (>20% Upside)
Win Rate only for recommendations where the analyst predicted a massive move (>20%).
Shows if they are right when they bet big.
Win Rate only for recommendations where the analyst predicted a massive move (>20%).
Shows if they are right when they bet big.
48%
10 W / 11 L
Long Wins
Success rate for BUY ratings
How often is the analyst right when saying "Buy"?
(Price went UP).
How often is the analyst right when saying "Buy"?
(Price went UP).
50%
16 W / 16 L
Short Wins
Success rate for SELL ratings
How often is the analyst right when saying "Sell"?
(Price went DOWN).
How often is the analyst right when saying "Sell"?
(Price went DOWN).
50%
2 W / 2 L
Coverage & Price Targets
| Date | Stock | Signal | Target | Start Price | Best Price (1Y) | Accuracy | Current Price |
|---|---|---|---|---|---|---|---|
| May 04, 2026 |
Moderna Inc
MRNA
|
SELL |
$38.00
Est. +19%
|
$46.87 | $43.90 (Low) |
Pending
|
$52.13
-11.2%
|
| Apr 08, 2026 |
BridgeBio Pharma Inc
BBIO
|
BUY |
$100.00
Est. +35%
|
$74.14 | $84.75 |
Pending
|
$68.00
-8.3%
|
| Mar 09, 2026 |
uniQure N.V.
QURE
|
BUY |
$35.00
Est. +95%
|
$17.99 | $31.00 |
Pending
|
$27.87
+54.9%
|
| Mar 02, 2026 |
uniQure N.V.
QURE
|
BUY |
$11.00
Est. +7%
|
$10.25 | $31.00 |
Target Met
|
$27.87
+171.9%
|
| Feb 17, 2026 |
Moderna Inc
MRNA
|
SELL |
$30.00
Est. +29%
|
$42.54 | $41.97 (Low) |
Pending
|
$52.13
-22.5%
|
| Dec 17, 2025 |
Ionis Pharmaceuticals Inc
IONS
|
BUY |
$95.00
Est. +21%
|
$78.37 | $86.74 |
Pending
|
$73.96
-5.6%
|
| Nov 21, 2025 |
Moderna Inc
MRNA
|
BUY |
$25.00
Est. +8%
|
$23.10 | $59.55 |
Target Met
|
$52.13
+125.7%
|
| Nov 11, 2025 |
CRISPR Therapeutics AG
CRSP
|
SELL |
$50.00
Est. +8%
|
$54.58 | $44.16 (Low) |
Target Met
|
$52.61
+3.6%
|
| Oct 28, 2025 |
Intellia Therapeutics Inc
NTLA
|
SELL |
$14.00
Est. +5%
|
$14.79 | $7.95 (Low) |
Target Met
|
$14.92
-0.9%
|
| Oct 28, 2025 |
Avidity Biosciences Inc
RNA
|
BUY |
$72.00
Est. +3%
|
$70.00 | $73.05 |
Precision Hit (±3%)
|
$12.75
-81.8%
|
| Oct 28, 2025 |
Biomarin Pharmaceutical Inc. - Registered Shares
BMRN
|
BUY |
$66.00
Est. +22%
|
$54.25 | $66.28 |
Bullseye Hit (±1%)
|
$55.65
+2.6%
|
| Aug 25, 2025 |
Argen X SE - ADR
ARGX
|
BUY |
$850.00
Est. +25%
|
$677.32 | $934.62 |
Target Met
|
$884.20
+30.5%
|
| Aug 08, 2025 |
Ascendis Pharma A/S - ADR
ASND
|
BUY |
$230.00
Est. +20%
|
$191.49 | $250.74 |
Target Met
|
$223.29
+16.6%
|
| Jan 07, 2025 |
uniQure N.V.
QURE
|
BUY |
$24.00
Est. +36%
|
$17.64 | $71.50 |
Target Met
|
$27.87
+58.0%
|
| Jan 07, 2025 |
Regenxbio Inc
RGNX
|
BUY |
$30.00
Est. +259%
|
$8.36 | $15.80 |
Miss
|
$7.07
-15.4%
|
| Nov 05, 2024 |
Adverum Biotechnologies Inc
ADVM
|
BUY |
$10.00
Est. +30%
|
$7.72 | $8.18 |
Miss
|
$4.36
-43.5%
|
| Oct 21, 2024 |
Korro Bio Inc.
KRRO
|
BUY |
$105.00
Est. +36%
|
$76.94 | $85.00 |
Miss
|
$11.61
-84.9%
|
| Oct 21, 2024 |
Wave Life Sciences Ltd.
WVE
|
BUY |
$15.00
Est. +1%
|
$14.80 | $16.74 |
Target Met
|
$6.00
-59.5%
|
| Sep 13, 2024 |
Moderna Inc
MRNA
|
BUY |
$75.00
Est. +8%
|
$69.68 | $75.36 |
Bullseye Hit (±1%)
|
$52.13
-25.2%
|
| Aug 26, 2024 |
Alnylam Pharmaceuticals Inc
ALNY
|
BUY |
$300.00
Est. +11%
|
$271.43 | $469.81 |
Target Met
|
$287.80
+6.0%
|
| Aug 13, 2024 |
MeiraGTx Holdings plc
MGTX
|
BUY |
$9.00
Est. +124%
|
$4.02 | $8.96 |
Bullseye Hit (±1%)
|
$9.75
+142.5%
|
| Aug 13, 2024 |
Adverum Biotechnologies Inc
ADVM
|
BUY |
$12.00
Est. +81%
|
$6.64 | $8.56 |
Miss
|
$4.36
-34.3%
|
| Aug 09, 2024 |
Intellia Therapeutics Inc
NTLA
|
BUY |
$54.00
Est. +141%
|
$22.38 | $24.16 |
Miss
|
$14.92
-33.3%
|
| Aug 06, 2024 |
CRISPR Therapeutics AG
CRSP
|
BUY |
$60.00
Est. +20%
|
$50.13 | $71.13 |
Target Met
|
$52.61
+4.9%
|
| Aug 05, 2024 |
Moderna Inc
MRNA
|
BUY |
$90.00
Est. +4%
|
$86.58 | $91.99 |
Precision Hit (±3%)
|
$52.13
-39.8%
|
| Jun 27, 2024 |
Alnylam Pharmaceuticals Inc
ALNY
|
BUY |
$265.00
Est. +8%
|
$245.17 | $326.03 |
Target Met
|
$287.80
+17.4%
|
| Jun 25, 2024 |
Alnylam Pharmaceuticals Inc
ALNY
|
BUY |
$250.00
Est. +12%
|
$222.90 | $326.03 |
Target Met
|
$287.80
+29.1%
|
| Jun 17, 2024 |
Ionis Pharmaceuticals Inc
IONS
|
BUY |
$70.00
Est. +72%
|
$40.63 | $52.34 |
Miss
|
$73.96
+82.0%
|
| Jun 12, 2024 |
Alnylam Pharmaceuticals Inc
ALNY
|
BUY |
$235.00
Est. +50%
|
$156.43 | $310.00 |
Target Met
|
$287.80
+84.0%
|
| May 31, 2024 |
Moderna Inc
MRNA
|
BUY |
$160.00
Est. +13%
|
$141.83 | $129.36 |
Miss
|
$52.13
-63.2%
|
| May 30, 2024 |
Arrowhead Pharmaceuticals Inc.
ARWR
|
BUY |
$50.00
Est. +119%
|
$22.87 | $30.41 |
Miss
|
$77.15
+237.3%
|
| May 03, 2024 |
Moderna Inc
MRNA
|
BUY |
$135.00
Est. +7%
|
$125.59 | $129.36 |
Miss
|
$52.13
-58.5%
|
| Mar 08, 2024 |
Regenxbio Inc
RGNX
|
BUY |
$35.00
Est. +54%
|
$22.75 | $15.36 |
Miss
|
$7.07
-68.9%
|
| Feb 24, 2022 |
Intellia Therapeutics Inc
NTLA
|
BUY |
$150.00
Est. +72%
|
$87.46 | - | - |
$14.92
-82.9%
|
| Feb 24, 2022 |
Ionis Pharmaceuticals Inc
IONS
|
BUY |
$67.00
Est. +106%
|
$32.49 | - | - |
$73.96
+127.6%
|
| Feb 10, 2022 |
Alnylam Pharmaceuticals Inc
ALNY
|
BUY |
$225.00
Est. +49%
|
$150.86 | - | - |
$287.80
+90.8%
|
Moderna Inc
MRNA
May 04, 2026
Signal & Target
SELL
$38.00
Start Price
$46.87
Best Price (1Y)
$43.90
Current Price
$52.13
Return
-11.2%
BridgeBio Pharma Inc
BBIO
Apr 08, 2026
Signal & Target
BUY
$100.00
Start Price
$74.14
Best Price (1Y)
$84.75
Current Price
$68.00
Return
-8.3%
uniQure N.V.
QURE
Mar 09, 2026
Signal & Target
BUY
$35.00
Start Price
$17.99
Best Price (1Y)
$31.00
Current Price
$27.87
Return
+54.9%
uniQure N.V.
QURE
Mar 02, 2026
Signal & Target
BUY
$11.00
Start Price
$10.25
Best Price (1Y)
$31.00
Current Price
$27.87
Return
+171.9%
Moderna Inc
MRNA
Feb 17, 2026
Signal & Target
SELL
$30.00
Start Price
$42.54
Best Price (1Y)
$41.97
Current Price
$52.13
Return
-22.5%
Ionis Pharmaceuticals Inc
IONS
Dec 17, 2025
Signal & Target
BUY
$95.00
Start Price
$78.37
Best Price (1Y)
$86.74
Current Price
$73.96
Return
-5.6%
Moderna Inc
MRNA
Nov 21, 2025
Signal & Target
BUY
$25.00
Start Price
$23.10
Best Price (1Y)
$59.55
Current Price
$52.13
Return
+125.7%
CRISPR Therapeutics AG
CRSP
Nov 11, 2025
Signal & Target
SELL
$50.00
Start Price
$54.58
Best Price (1Y)
$44.16
Current Price
$52.61
Return
+3.6%
Intellia Therapeutics Inc
NTLA
Oct 28, 2025
Signal & Target
SELL
$14.00
Start Price
$14.79
Best Price (1Y)
$7.95
Current Price
$14.92
Return
-0.9%
Avidity Biosciences Inc
RNA
Oct 28, 2025
Signal & Target
BUY
$72.00
Start Price
$70.00
Best Price (1Y)
$73.05
Current Price
$12.75
Return
-81.8%
Signal & Target
BUY
$66.00
Start Price
$54.25
Best Price (1Y)
$66.28
Current Price
$55.65
Return
+2.6%
Argen X SE - ADR
ARGX
Aug 25, 2025
Signal & Target
BUY
$850.00
Start Price
$677.32
Best Price (1Y)
$934.62
Current Price
$884.20
Return
+30.5%
Ascendis Pharma A/S - ADR
ASND
Aug 08, 2025
Signal & Target
BUY
$230.00
Start Price
$191.49
Best Price (1Y)
$250.74
Current Price
$223.29
Return
+16.6%
uniQure N.V.
QURE
Jan 07, 2025
Signal & Target
BUY
$24.00
Start Price
$17.64
Best Price (1Y)
$71.50
Current Price
$27.87
Return
+58.0%
Regenxbio Inc
RGNX
Jan 07, 2025
Signal & Target
BUY
$30.00
Start Price
$8.36
Best Price (1Y)
$15.80
Current Price
$7.07
Return
-15.4%
Adverum Biotechnologies Inc
ADVM
Nov 05, 2024
Signal & Target
BUY
$10.00
Start Price
$7.72
Best Price (1Y)
$8.18
Current Price
$4.36
Return
-43.5%
Korro Bio Inc.
KRRO
Oct 21, 2024
Signal & Target
BUY
$105.00
Start Price
$76.94
Best Price (1Y)
$85.00
Current Price
$11.61
Return
-84.9%
Wave Life Sciences Ltd.
WVE
Oct 21, 2024
Signal & Target
BUY
$15.00
Start Price
$14.80
Best Price (1Y)
$16.74
Current Price
$6.00
Return
-59.5%
Moderna Inc
MRNA
Sep 13, 2024
Signal & Target
BUY
$75.00
Start Price
$69.68
Best Price (1Y)
$75.36
Current Price
$52.13
Return
-25.2%
Alnylam Pharmaceuticals Inc
ALNY
Aug 26, 2024
Signal & Target
BUY
$300.00
Start Price
$271.43
Best Price (1Y)
$469.81
Current Price
$287.80
Return
+6.0%
MeiraGTx Holdings plc
MGTX
Aug 13, 2024
Signal & Target
BUY
$9.00
Start Price
$4.02
Best Price (1Y)
$8.96
Current Price
$9.75
Return
+142.5%
Adverum Biotechnologies Inc
ADVM
Aug 13, 2024
Signal & Target
BUY
$12.00
Start Price
$6.64
Best Price (1Y)
$8.56
Current Price
$4.36
Return
-34.3%
Intellia Therapeutics Inc
NTLA
Aug 09, 2024
Signal & Target
BUY
$54.00
Start Price
$22.38
Best Price (1Y)
$24.16
Current Price
$14.92
Return
-33.3%
CRISPR Therapeutics AG
CRSP
Aug 06, 2024
Signal & Target
BUY
$60.00
Start Price
$50.13
Best Price (1Y)
$71.13
Current Price
$52.61
Return
+4.9%
Moderna Inc
MRNA
Aug 05, 2024
Signal & Target
BUY
$90.00
Start Price
$86.58
Best Price (1Y)
$91.99
Current Price
$52.13
Return
-39.8%
Alnylam Pharmaceuticals Inc
ALNY
Jun 27, 2024
Signal & Target
BUY
$265.00
Start Price
$245.17
Best Price (1Y)
$326.03
Current Price
$287.80
Return
+17.4%
Alnylam Pharmaceuticals Inc
ALNY
Jun 25, 2024
Signal & Target
BUY
$250.00
Start Price
$222.90
Best Price (1Y)
$326.03
Current Price
$287.80
Return
+29.1%
Ionis Pharmaceuticals Inc
IONS
Jun 17, 2024
Signal & Target
BUY
$70.00
Start Price
$40.63
Best Price (1Y)
$52.34
Current Price
$73.96
Return
+82.0%
Alnylam Pharmaceuticals Inc
ALNY
Jun 12, 2024
Signal & Target
BUY
$235.00
Start Price
$156.43
Best Price (1Y)
$310.00
Current Price
$287.80
Return
+84.0%
Moderna Inc
MRNA
May 31, 2024
Signal & Target
BUY
$160.00
Start Price
$141.83
Best Price (1Y)
$129.36
Current Price
$52.13
Return
-63.2%
Arrowhead Pharmaceuticals Inc.
ARWR
May 30, 2024
Signal & Target
BUY
$50.00
Start Price
$22.87
Best Price (1Y)
$30.41
Current Price
$77.15
Return
+237.3%
Moderna Inc
MRNA
May 03, 2024
Signal & Target
BUY
$135.00
Start Price
$125.59
Best Price (1Y)
$129.36
Current Price
$52.13
Return
-58.5%
Regenxbio Inc
RGNX
Mar 08, 2024
Signal & Target
BUY
$35.00
Start Price
$22.75
Best Price (1Y)
$15.36
Current Price
$7.07
Return
-68.9%
Intellia Therapeutics Inc
NTLA
Feb 24, 2022
Signal & Target
BUY
$150.00
Start Price
$87.46
Best Price (1Y)
-
Current Price
$14.92
Return
-82.9%
Ionis Pharmaceuticals Inc
IONS
Feb 24, 2022
Signal & Target
BUY
$67.00
Start Price
$32.49
Best Price (1Y)
-
Current Price
$73.96
Return
+127.6%
Alnylam Pharmaceuticals Inc
ALNY
Feb 10, 2022
Signal & Target
BUY
$225.00
Start Price
$150.86
Best Price (1Y)
-
Current Price
$287.80
Return
+90.8%