Upstream Bio, Inc.

Upstream Bio, Inc.

UPB - Insider Information

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Market Cap$255.77M
Close$

Compare to Similar Companies

P/E RatioDividendsReturn on EquityPrice-to-SalesDebt-to-Equity
Upstream Bio, Inc.Upstream Bio, Inc.-1.6----
$25.00

Target Price by Analysts

796.1% upsideUpstream Bio Target Price DetailsTarget Price
$-0.65

Current Fair Value

123.4% downside

Overvalued by 123.4% based on the discounted cash flow analysis.

Insider Trades

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Congress Trades

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Share Statistics

Market cap$255.77 Million
Enterprise Value-
Earnings per Share$-2.66
Beta1.39
Outstanding Shares54,567,976

Return

Return on EquityNaN%ROE
Return on AssetsNaN%
Return on Invested CapitalNaN%

Valuation & Multiples

P/E Ratio-1.62P/E Ratio
PEG245.35PEG
Price to Sales-Price to Sales
Price to Book Ratio-Price to Book Ratio
Enterprise Value to Revenue-
Enterprise Value to EBIT-
Enterprise Value to Net Income-
Total Debt to Enterprise-
Debt to Equity-Debt to Equity

Revenue Sources

No data

Last Earnings Call

Report Date
August 11, 2026
EPS Estimate
$-0.78
Consensus analyst estimate
Revenue Estimate
$431,143
Consensus analyst estimate

Next Earnings Call

Expected Date
November 4, 2026
EPS Estimate
$-0.73
Consensus analyst estimate
Revenue Estimate
$522,455
Consensus analyst estimate

Institutional Put/Call Ratio

Compares institutional put options with call options. At 0.00, the ratio is below 1, so institutions hold more calls than puts.

Put/Call Ratio0.00000%
Total Calls-▼ 100.00%
Total Puts-

Institutional Ownership

Holdings and activity of institutional investors.

Ownership %0.00%▼ 93.16%
Total Invested$9,855▼ 100.00%
Investors Holding3▼ 150.00%

About Upstream Bio, Inc.

75 employees
CEO: E. Rand Sutherland

Upstream Bio, Inc. is a biotechnology company in the clinical development stage, dedicated to innovating therapies for inflammatory conditions, particularly those affecting the severe respiratory system. Its pipeline notably features ver...

Upstream Bio Insider Information FAQ

Stockcircle shows 10 open-market insider sales for Upstream Bio in the last six months from SEC Form 4 reports by executives, directors, and other insiders.

Form 4 insider trades are added as new filings are imported. Top investor 13F holdings refresh after each quarterly filing cycle. Politician trade disclosures are added when new reports are published on Stockcircle.