Spyre Therapeutics Profit Margin

As of the most recent data (June 2026), SYRE shows a profit margin of -197.71%. That is below the Healthcare sector average of 13.76%. Scroll down for historical charts and peer comparison views.

The Healthcare sector average profit margin is about 13.76%. Spyre Therapeutics is at -197.71%, which is lower that average. That is roughly 1536.8% below the sector mean. Use the comparison chart on this page to see how SYRE stacks up against individual peers as well.

Check the historical chart to see whether SYRE's profit margin is trending up or down. Improvement over multiple periods is generally more meaningful than a single strong quarter. Compare Spyre Therapeutics with peers to see if the move is company-specific or sector-wide.

Besides this profit margin page, Stockcircle has Spyre Therapeutics's full stock overview, other financial metrics, insider and congress trade tabs, and tools to follow the stock. Together they help you connect profit margin (currently -197.71%) with ownership activity and broader fundamentals.

The Healthcare average profit margin is about 13.76%, while SYRE is at -197.71%. Typical ranges vary by sub-industry, so always sanity-check against the closest competitors, not just the whole sector bucket.