Septerna, Inc.

Septerna, Inc.

SEPN

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Market Cap$1.8B
Close$

Compare to Similar Companies

P/E RatioDividendsReturn on EquityPrice-to-SalesDebt-to-Equity
Septerna, Inc.Septerna, Inc.-74.1--6%22.10.3
$50.25

Target Price by Analysts

13.7% upsideSepterna Target Price DetailsTarget Price
$-33.12

Current Fair Value

174.9% downside

Overvalued by 174.9% based on the discounted cash flow analysis.

Share Statistics

Market cap$1.80 Billion
Enterprise Value$1.82 Billion
Dividend Yield$- (-)
Earnings per Share$-1.1
Beta2.28
Outstanding Shares45,040,075

Return

Return on Equity-6.27%ROE
Return on Assets-4.28%
Return on Invested Capital-10.52%

Valuation & Multiples

P/E Ratio-74.07P/E Ratio
PEG155.87PEG
Price to Sales22.1Price to Sales
Price to Book Ratio5.53Price to Book Ratio
Enterprise Value to Revenue18.42
Enterprise Value to EBIT-35.53
Enterprise Value to Net Income-76
Total Debt to Enterprise0.06
Debt to Equity0.27Debt to Equity

Revenue Sources

No data

Insider Trades

Last Earnings Call

Report Date
August 10, 2026
EPS Estimate
$-0.43
Average shareholder expectation
Revenue Estimate
$19.22 M
Average shareholder expectation

Next Earnings Call

Expected Date
November 9, 2026
EPS Estimate
$-0.52
Average shareholder expectation
Revenue Estimate
$19.22 M
Average shareholder expectation

Institutional Put/Call Ratio

Market sentiment based on institutional option activity.

Put/Call Ratio0.3782 37.82%
Total Calls1,041,000 1326.03%
Total Puts393,752 Infinity%

Institutional Ownership

Holdings and activity of institutional investors.

Ownership %105.92% 3.76%
Total Invested$1.59B 44.49%
Investors Holding164 39.00%

ESG Score

No data

About Septerna, Inc.

75 employees
CEO: Dr. Jeffrey T. Finer M.D., Ph.D.

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products candidates for the treatment of endocrinology, immunology and inflammation, and metabolic disea...