Septerna, Inc.

Septerna, Inc.

SEPN

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Market Cap$1.36B
Close$

Compare to Similar Companies

P/E RatioDividendsReturn on EquityPrice-to-SalesDebt-to-Equity
Septerna, Inc.Septerna, Inc.-37.5--10%30.60.2
$60.00

Target Price by Analysts

96.4% upsideSepterna Target Price DetailsTarget Price
$-20.58

Current Fair Value

167.4% downside

Overvalued by 167.4% based on the discounted cash flow analysis.

Share Statistics

Market cap$1.36 Billion
Enterprise Value$1.37 Billion
Dividend Yield$- (-)
Earnings per Share$-1.1
Beta2.2
Outstanding Shares44,758,800

Return

Return on Equity-9.52%ROE
Return on Assets-6.33%
Return on Invested Capital-13.87%

Valuation & Multiples

P/E Ratio-37.51P/E Ratio
PEG62.74PEG
Price to Sales30.55Price to Sales
Price to Book Ratio3.82Price to Book Ratio
Enterprise Value to Revenue19
Enterprise Value to EBIT-20.13
Enterprise Value to Net Income-39
Total Debt to Enterprise0.06
Debt to Equity0.22Debt to Equity

Revenue Sources

No data

Insider Trades

Last Earnings Call

Report Date
May 21, 2026
EPS Estimate
$-0.42
Average shareholder expectation
Revenue Estimate
$16.98 M
Average shareholder expectation

Next Earnings Call

Expected Date
August 10, 2026
EPS Estimate
$-0.42
Average shareholder expectation
Revenue Estimate
$18.50 M
Average shareholder expectation

Institutional Put/Call Ratio

Market sentiment based on institutional option activity.

Put/Call Ratio0.0000 221.46%
Total Calls73,000 9.99%
Total Puts- 100.00%

Institutional Ownership

Holdings and activity of institutional investors.

Ownership %103.31% 0.50%
Total Invested$1.10B 13.55%
Investors Holding125 2.00%

ESG Score

No data

About Septerna, Inc.

75 employees
CEO: Dr. Jeffrey T. Finer M.D., Ph.D.

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products candidates for the treatment of endocrinology, immunology and inflammation, and metabolic disea...