Septerna, Inc.

Septerna, Inc.

SEPN

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Market Cap$1.7B
Close$

Compare to Similar Companies

P/E RatioDividendsReturn on EquityPrice-to-SalesDebt-to-Equity
Septerna, Inc.Septerna, Inc.-69.8--6%18.90.3
$50.25

Target Price by Analysts

33.3% upsideSepterna Target Price DetailsTarget Price
$-30.86

Current Fair Value

181.8% downside

Overvalued by 181.8% based on the discounted cash flow analysis.

Share Statistics

Market cap$1.70 Billion
Enterprise Value$1.72 Billion
Dividend Yield$- (-)
Earnings per Share$-1.1
Beta2.29
Outstanding Shares45,040,075

Return

Return on Equity-6.27%ROE
Return on Assets-4.28%
Return on Invested Capital-10.52%

Valuation & Multiples

P/E Ratio-69.83P/E Ratio
PEG146.94PEG
Price to Sales18.86Price to Sales
Price to Book Ratio4.71Price to Book Ratio
Enterprise Value to Revenue17.38
Enterprise Value to EBIT-33.51
Enterprise Value to Net Income-71
Total Debt to Enterprise0.06
Debt to Equity0.27Debt to Equity

Revenue Sources

No data

Insider Trades

Last Earnings Call

Report Date
August 10, 2026
EPS Estimate
$-0.43
Average shareholder expectation
Revenue Estimate
$19.22 M
Average shareholder expectation

Next Earnings Call

Expected Date
November 9, 2026
EPS Estimate
$-0.41
Average shareholder expectation
Revenue Estimate
$20.78 M
Average shareholder expectation

Institutional Put/Call Ratio

Market sentiment based on institutional option activity.

Put/Call Ratio0.3782▲ 37.82%
Total Calls1,041,000▲ 1326.03%
Total Puts393,752▲ Infinity%

Institutional Ownership

Holdings and activity of institutional investors.

Ownership %105.31%▲ 3.16%
Total Invested$1.59B▲ 44.56%
Investors Holding166▲ 41.00%

ESG Score

No data

About Septerna, Inc.

75 employees
CEO: Dr. Jeffrey T. Finer M.D., Ph.D.

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products candidates for the treatment of endocrinology, immunology and inflammation, and metabolic disea...