Personalis Profit Margin

The latest profit margin for PSNL is -290.84% as of June 2026. That compares with -113.7% in the prior-year period — down 155.8% year over year. That is below the Healthcare sector average of 10.58%. Investors often review this figure alongside Personalis's historical trend and sector peers before judging valuation or financial health.

Over the past year, PSNL's profit margin moved from -113.7% to -290.84% — a 155.8% year-over-year decrease. If the trend continues in the same direction for several quarters, it can signal a meaningful shift in Personalis's valuation or profitability profile.

Against Healthcare companies, PSNL currently prints -290.84% for profit margin, while the sector average sits near 10.58%. That is roughly 2848.8% below the sector mean. Large gaps often invite a closer look at Personalis's growth, margins, and balance sheet.

Profit Margin shows how effectively Personalis converts resources into returns. At -290.84%, PSNL may look efficient or underperforming depending on peer benchmarks and trend direction. That compares with -113.7% in the prior-year period — down 155.8% year over year. Pair the percentage with revenue growth and leverage for a fuller health check.

After noting PSNL's profit margin (-290.84%), review year-over-year change from -113.7%, peer averages, and a few neighboring metrics such as revenue, margins, or valuation multiples. That combination usually beats staring at a single figure. The navigation links on this page jump you to those related views.