Agios Pharmaceuticals Profit Margin

As of the most recent data (June 2026), AGIO shows a profit margin of -418.24%. That compares with 1590.42% in the prior-year period — down 126.3% year over year. That is below the Healthcare sector average of 15.29%. Scroll down for historical charts and peer comparison views.

Compared with the year-ago period, AGIO's profit margin is now -418.24% (was 1590.42%) — a 126.3% year-over-year decrease. Pairing that YoY change with peer averages gives a clearer picture of whether Agios Pharmaceuticals is outperforming or lagging.

The Healthcare sector average profit margin is about 15.29%. Agios Pharmaceuticals is at -418.24%, which is lower that average. That is roughly 2834.8% below the sector mean. Use the comparison chart on this page to see how AGIO stacks up against individual peers as well.

That compares with 1590.42% in the prior-year period — down 126.3% year over year. Improvement over multiple periods is generally more meaningful than a single strong quarter. Compare Agios Pharmaceuticals with peers to see if the move is company-specific or sector-wide.

Besides this profit margin page, Stockcircle has Agios Pharmaceuticals's full stock overview, other financial metrics, insider and congress trade tabs, and tools to follow the stock. Together they help you connect profit margin (currently -418.24%) with ownership activity and broader fundamentals.