Septerna, Inc.

Septerna, Inc.

SEPN

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Market Cap$2.01B
Close$

Compare to Similar Companies

P/E RatioDividendsReturn on EquityPrice-to-SalesDebt-to-Equity
Septerna, Inc.Septerna, Inc.-82.4--6%22.60.3
$48.25

Target Price by Analysts

6.9% upsideSepterna Target Price DetailsTarget Price
$-33.21

Current Fair Value

173.6% downside

Overvalued by 173.6% based on the discounted cash flow analysis.

Share Statistics

Market cap$2.01 Billion
Enterprise Value$2.02 Billion
Dividend Yield$- (-)
Earnings per Share$-1.1
Beta2.28
Outstanding Shares45,040,075

Return

Return on Equity-6.27%ROE
Return on Assets-4.28%
Return on Invested Capital-10.52%

Valuation & Multiples

P/E Ratio-82.41P/E Ratio
PEG173.4PEG
Price to Sales22.57Price to Sales
Price to Book Ratio5.64Price to Book Ratio
Enterprise Value to Revenue20.47
Enterprise Value to EBIT-39.48
Enterprise Value to Net Income-84
Total Debt to Enterprise0.05
Debt to Equity0.27Debt to Equity

Revenue Sources

No data

Insider Trades

Last Earnings Call

Report Date
August 10, 2026
EPS Estimate
$-0.43
Average shareholder expectation
Revenue Estimate
$19.22 M
Average shareholder expectation

Next Earnings Call

Expected Date
November 9, 2026
EPS Estimate
$-0.60
Average shareholder expectation
Revenue Estimate
$21.48 M
Average shareholder expectation

Institutional Put/Call Ratio

Market sentiment based on institutional option activity.

Put/Call Ratio0.00000%
Total Calls- 100.00%
Total Puts152 Infinity%

Institutional Ownership

Holdings and activity of institutional investors.

Ownership %30.28% 71.87%
Total Invested$453.87M 58.69%
Investors Holding42 83.00%

ESG Score

No data

About Septerna, Inc.

75 employees
CEO: Dr. Jeffrey T. Finer M.D., Ph.D.

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products candidates for the treatment of endocrinology, immunology and inflammation, and metabolic disea...