USA Passive

iShares U.S. Pharmaceuticals ETF

The iShares U.S. Pharmaceuticals ETF (the “Fund”) seeks to track the investment results of an index composed of U.S. equities in the pharmaceuticals sector.

$101.07

Key Metrics

TER 0.37% per year
Distribution policy Distributing
Fund size USD 1,138 M
Inception date April 30, 2006
Holdings 59
Fund currency USD
Fund domicile US
Provider iShares
For full official fund details, factsheets, and holdings, visit ishares.com (opens in new tab).

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Historical Return

Last updated: Sep 01, 2026
1 Year +45.3% +1.5% Div
3 Years (avg.) -18.4% +1.5% Div
5 Years (avg.) -11.8% +1.5% Div

Risk & Analysis Metrics

Last updated: Sep 01, 2026

Volatility

16.69% 1 Year
41.19% 3 Years
33.69% 5 Years
27.64% 10 Years

Max Drawdown

-8.77% 1 Year
-70.76% 3 Years
-70.76% 5 Years
-70.76% 10 Years

Sharpe Ratio

1.84 1 Year
-0.20 3 Years
-0.20 5 Years
-0.07 10 Years

Return Triangle (Heatmap)

Last updated: Sep 01, 2026
2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025
2011 18.4% 14.4% 21.4% 23.2% 19.7% 14.0% 13.1% 9.9% 10.3% 10.4% 10.6% 9.1% 8.3% -0.1% 1.7%
2012 10.6% 22.9% 24.9% 20.0% 13.2% 12.2% 8.7% 9.3% 9.6% 9.8% 8.3% 7.5% -1.4% 0.6%
2013 36.6% 32.8% 23.3% 13.9% 12.5% 8.4% 9.1% 9.5% 9.7% 8.1% 7.3% -2.3% -0.2%
2014 29.1% 17.2% 7.1% 7.2% 3.5% 5.1% 6.1% 6.8% 5.3% 4.7% -5.2% -2.7%
2015 6.4% -2.4% 0.8% -2.0% 0.9% 2.6% 3.9% 2.6% 2.3% -8.1% -5.2%
2016 -10.4% -1.9% -4.7% -0.4% 1.9% 3.5% 2.1% 1.8% -9.6% -6.3%
2017 7.4% -1.6% 3.2% 5.3% 6.6% 4.4% 3.7% -9.5% -5.8%
2018 -9.9% 1.1% 4.5% 6.4% 3.8% 3.1% -11.7% -7.4%
2019 13.5% 12.6% 12.4% 7.5% 5.9% -12.0% -7.0%
2020 11.7% 11.9% 5.6% 4.0% -16.3% -10.0%
2021 12.0% 2.6% 1.6% -22.2% -13.9%
2022 -6.0% -3.2% -31.1% -19.3%
2023 -0.4% -41.0% -23.3%
2024 -65.0% -32.7%
2025 29.3%

Distributions

*by ETF Portfolio Weight Last updated: Sep 01, 2026

Profit Margin Distribution

< 0%
9%
1y 3y N/A N/A
0 - 5%
1%
1y 3y N/A N/A
5 - 10%
1%
1y 3y N/A N/A
10 - 15%
1%
1y 3y N/A N/A
15 - 20%
7%
1y 3y N/A N/A
20 - 30%
44%
1y 3y N/A N/A
30 - 40%
38%
1y 3y N/A N/A
> 40%
2%
1y 3y N/A N/A

P/E Ratio Distribution

< 0
13%
1y 3y N/A N/A
0 - 10
0%
1y 3y N/A N/A
10 - 15
12%
1y 3y N/A N/A
15 - 20
6%
1y 3y N/A N/A
20 - 25
0%
1y 3y N/A N/A
25 - 35
39%
1y 3y N/A N/A
35 - 50
30%
1y 3y N/A N/A
> 50
0%
1y 3y N/A N/A

Discounted Cash Flow

Weighted Average Undervaluation
N/A
Undervalued
> 60%
0%
1y 3y N/A N/A
45 - 60%
0%
1y 3y N/A N/A
30 - 45%
0%
1y 3y N/A N/A
15 - 30%
0%
1y 3y N/A N/A
Fair (&plusmn;15%)
0%
1y 3y N/A N/A
Overvalued
15 - 30%
0%
1y 3y N/A N/A
30 - 45%
0%
1y 3y N/A N/A
45 - 60%
0%
1y 3y N/A N/A
> 60%
0%
1y 3y N/A N/A

Market Cap Size Distribution

Micro Cap
0.1%
1y 3y N/A N/A
Small Cap
2.7%
1y 3y N/A N/A
Mid Cap
12.3%
1y 3y N/A N/A
Large Cap
26.9%
1y 3y N/A N/A
Mega Cap
58.1%
1y 3y N/A N/A
Micro: < $300M Small: $300M–$2B Mid: $2B–$10B Large: $10B–$200B Mega: > $200B

Portfolio Concentration

*by ETF Portfolio Weight Last updated: Sep 01, 2026
76.3% Top 5 Holdings
89.4% Top 10 Holdings
100.0% Top 50 Holdings
100.0% Top 100 Holdings
Top 5 Companies
JNJ Johnson & Johnson
30.3%
LLY Lilly(Eli) & Co
27.7%
RPRX Royalty Pharma plc
6.2%
BMY Bristol-Myers Squibb Co.
6.1%
ZTS Zoetis Inc
6.0%

Latest News

6 days ago • zacks.com

Johnson & Johnson (JNJ) Sees a More Significant Dip Than Broader Market: Some Facts to Know

Johnson & Johnson (JNJ) reached $269.12 at the closing of the latest trading day, reflecting a -2.22% change compared to its last close.
6 days ago • fool.com

Does iShares Pharma ETF Offer Superior Returns to Invesco's Equal Weight Healthcare Fund?

IHE's concentrated pharma holdings delivered 50% returns over one year, while RSPH's equal-weight healthcare approach generated 29%. Risk profiles ...
6 days ago • fool.com

Is the iShares Pharmaceuticals ETF or iShares Healthcare ETF the Better Fund for 2026?

IHE's concentrated pharma focus delivered 50% gains versus IYH's 27.4%, though the broader healthcare fund offers more diversification and $3.9B in...

Average metrics of all companies in portfolio

Last updated: Sep 13, 2026
Market
Average
Market Cap The market value of the company. It's calculated by multiplying the share price by the number of outstanding shares. $531B -
Dividend Yield Yearly payout to shareholders per share. The percentage indicates the payout in relation to the share price. 1.29% 2.01%
Beta Indicates the relationship between the price performance of a share and the market. 0.45 -
P/E Ratio Ratio between share price and earnings per share. A low ratio could indicate that the stock is undervalued or investors aren't expecting high growth. A high ratio could indicate that the stock is overvalued or investors are expecting high growth. 29.9 22.99
Negative P/E Ratio a negative P/E ratio shows that the company is not profitable, and it shows how many years it would take the company to lose its entire market capitalisation if it did not change anything -41.03 -
Profitable Companies 86% -
PEG The ratio between the P/E ratio and the growth rate of the company's earnings per share in the last twelve months. A lower PEG could mean that a stock is undervalued. 9.54 18.8
Price to Sales Ratio Market cap divided by the revenue in the most recent year. 8.32 9.13
Price to Book Ratio Price to Book Ratio is the Market cap divided by the Book value of the company 14.04 11.88
Market
Average
Enterprise Value to EBIT Enterprise Value divided by EBIT 21.82 12.43
Enterprise Value to Revenue Enterprise value divided by revenue 9.02 12.4
Total Debt to Enterprise Value Total debt divided by enterprise value 0.1 0.04
Debt to Equity A higher ratio indicates a higher risk. However, the ratio is difficult to compare between industries where common amounts of debt vary. 1.04 0.32
Profit Margin Net income divided by revenue of the last 4 quarters. It indicates the company's profitability. 24.66% 21.44%
Quarterly Earnings Growth (YoY) The rate at which the company's net income has increased to the same quarter one year ago. +28.7% +54.3%
Return on Equity Equity divided by market cap. 37.57% 2.03%
Return on Assets Indicates a company's profitability in relation to its total assets. 9.01% 4.04%
Return on Invested Capital Return on invested capital (ROIC) is net income after dividends divided by the sum of debt and equity. It shows how effective a company is at turning capital invested by shareholders and other debtholders into profits. 17.68% 3.73%

Sectors

Manufacturing 71.0%
Healthcare 2.6%
Professional, Scientific, and Technical Services 0.9%
Other 25.4%

Countries

United States 95.9%
Ireland 3.8%
Other 0.3%

Stock Screener

Select filters to narrow down the 31 investments below

31 companies

Limit holdings to companies in a single sector.

$0B >$1T

Ratio between share price and earnings per share. A low ratio could indicate undervaluation.

<0 >50

Ratio of dividends in the last 12 months to current share price.

0% 3%

Revenue increase compared to the same quarter one year ago.

0% 30%

Net income increase compared to the same quarter one year ago.

0% 30%

Profitability of the last quarter.

<-30% >30%

A higher ratio indicates a higher risk. The ratio is difficult to compare between industries.

<0 >3

Discounted cash flow valuation vs. current price. Positive = undervalued, negative = overvalued.

<-50% >+100%
Market Cap
P/E Ratio
Dividends Ratio of dividends in the last 12 months to current share price
Total Investment
Weight

Johnson & Johnson

JNJ - Manufacturing

Johnson & Johnson

JNJ - Manufacturing
Market Cap $640.02B
P/E Ratio 30.7
Dividends 2.0%
Total Investment $255.48M
Weight 22.44%

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Lilly(Eli) & Co

LLY - Manufacturing

Lilly(Eli) & Co

LLY - Manufacturing
Market Cap $1.05T
P/E Ratio 37.4
Dividends 0.6%
Total Investment $253.23M
Weight 22.25%

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Bristol-Myers Squibb Co.

BMY - Manufacturing

Bristol-Myers Squibb Co.

BMY - Manufacturing
Market Cap $130B
P/E Ratio 14.0
Dividends 3.9%
Total Investment $49.73M
Weight 4.37%

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Royalty Pharma plc - Ordinary Shares - Class A

RPRX - Manufacturing

Royalty Pharma plc - Ordinary Shares - Class A

RPRX - Manufacturing
Market Cap $25.98B
P/E Ratio 24.3
Dividends 1.6%
Total Investment $49.35M
Weight 4.33%

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Zoetis Inc - Ordinary Shares - Class A

ZTS - Manufacturing

Zoetis Inc - Ordinary Shares - Class A

ZTS - Manufacturing
Market Cap $30.6B
P/E Ratio 12.0
Dividends 2.9%
Total Investment $42.42M
Weight 3.73%

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Jazz Pharmaceuticals plc

JAZZ - Manufacturing

Jazz Pharmaceuticals plc

JAZZ - Manufacturing
Market Cap $15.44B
P/E Ratio 16.2
Dividends 0.0%
Total Investment $39.28M
Weight 3.45%

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Elanco Animal Health Inc

ELAN - Manufacturing

Elanco Animal Health Inc

ELAN - Manufacturing
Market Cap $11.57B
P/E Ratio -56.5
Dividends 0.0%
Total Investment $31.94M
Weight 2.81%

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Ligand Pharmaceuticals, Inc. - Ordinary Shares - Class B

LGND - Manufacturing

Ligand Pharmaceuticals, Inc. - Ordinary Shares - Class B

LGND - Manufacturing
Market Cap $5.7B
P/E Ratio 28.4
Dividends 0.0%
Total Investment $16.46M
Weight 1.45%

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Mind Medicine Inc

MNMD - Healthcare

Mind Medicine Inc

MNMD - Healthcare
Market Cap $5.16B
P/E Ratio -11.3
Dividends 0.0%
Total Investment $15.81M
Weight 1.39%

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Liquidia Corp

LQDA - Manufacturing

Liquidia Corp

LQDA - Manufacturing
Market Cap $5.94B
P/E Ratio 42.5
Dividends 0.0%
Total Investment $14.55M
Weight 1.28%

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Crinetics Pharmaceuticals Inc

CRNX - Professional, Scientific, and Technical Services

Crinetics Pharmaceuticals Inc

CRNX - Professional, Scientific, and Technical Services
Market Cap $9B
P/E Ratio -16.8
Dividends 0.0%
Total Investment $10.25M
Weight 0.90%

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Organon & Co.

OGN - Manufacturing

Organon & Co.

OGN - Manufacturing
Market Cap $3.58B
P/E Ratio 17.3
Dividends 0.6%
Total Investment $9.25M
Weight 0.81%

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Edgewise Therapeutics Inc

EWTX - Manufacturing

Edgewise Therapeutics Inc

EWTX - Manufacturing
Market Cap $4.78B
P/E Ratio -24.0
Dividends 0.0%
Total Investment $7.96M
Weight 0.70%

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Enliven Therapeutics Inc

ELVN - Manufacturing

Enliven Therapeutics Inc

ELVN - Manufacturing
Market Cap $3.88B
P/E Ratio -33.1
Dividends 0.0%
Total Investment $7.18M
Weight 0.63%

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Tarsus Pharmaceuticals Inc

TARS - Manufacturing

Tarsus Pharmaceuticals Inc

TARS - Manufacturing
Market Cap $3.41B
P/E Ratio -72.8
Dividends 0.0%
Total Investment $6.47M
Weight 0.57%

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Veradermics, Incorporated

MANE - Healthcare

Veradermics, Incorporated

MANE - Healthcare
Market Cap $4.13B
P/E Ratio -46.2
Dividends 0.0%
Total Investment $6.4M
Weight 0.56%

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Alumis Inc.

ALMS

Alumis Inc.

ALMS
Market Cap $1.13B
P/E Ratio -2.4
Dividends 0.0%
Total Investment $6.23M
Weight 0.55%

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Trevi Therapeutics Inc

TRVI - Manufacturing

Trevi Therapeutics Inc

TRVI - Manufacturing
Market Cap $2.26B
P/E Ratio -47.1
Dividends 0.0%
Total Investment $5.72M
Weight 0.50%

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Amylyx Pharmaceuticals Inc

AMLX

Amylyx Pharmaceuticals Inc

AMLX
Market Cap $3.52B
P/E Ratio -22.4
Dividends 0.0%
Total Investment $3.94M
Weight 0.35%

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ANI Pharmaceuticals Inc

ANIP - Manufacturing

ANI Pharmaceuticals Inc

ANIP - Manufacturing
Market Cap $1.6B
P/E Ratio 14.5
Dividends 0.0%
Total Investment $3.92M
Weight 0.34%

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