Paul Matteis Score: 38
Analyst at
Stifel Nicolaus
Avg Return (Buy)
How much profit would you make?
Calculates the average return of all BUY recommendations after exactly 1 year (or today if newer).
Note: Sell ratings are ignored here to focus on investment potential.
Calculates the average return of all BUY recommendations after exactly 1 year (or today if newer).
Note: Sell ratings are ignored here to focus on investment potential.
+22.2%
1 Year Cap
Win Rate
How often is the direction correct?
Percentage of trades that are currently profitable.
• Buy: Stock price went UP 📈
• Sell: Stock price went DOWN 📉
Percentage of trades that are currently profitable.
• Buy: Stock price went UP 📈
• Sell: Stock price went DOWN 📉
58%
19 W / 14 L
Target Met
How often was the target reached?
Hits vs. Total.
Hits vs. Total.
64%
14 W / 8 L
Precision Hit
How often precise (±3%)?
Hits vs. Total.
Hits vs. Total.
23%
5 W / 17 L
Bullseye Hit
How often perfect (±1%)?
Hits vs. Total.
Hits vs. Total.
9%
2 W / 20 L
High Conviction
The "Brave" Trades (>20% Upside)
Win Rate only for recommendations where the analyst predicted a massive move (>20%).
Shows if they are right when they bet big.
Win Rate only for recommendations where the analyst predicted a massive move (>20%).
Shows if they are right when they bet big.
64%
14 W / 8 L
Long Wins
Success rate for BUY ratings
How often is the analyst right when saying "Buy"?
(Price went UP).
How often is the analyst right when saying "Buy"?
(Price went UP).
57%
16 W / 12 L
Short Wins
Success rate for SELL ratings
How often is the analyst right when saying "Sell"?
(Price went DOWN).
How often is the analyst right when saying "Sell"?
(Price went DOWN).
60%
3 W / 2 L
Coverage & Price Targets
| Date | Stock | Signal | Target | Start Price | Best Price (1Y) | Accuracy | Current Price |
|---|---|---|---|---|---|---|---|
| Jun 15, 2026 |
Rhythm Pharmaceuticals Inc.
RYTM
|
BUY |
$133.00
Est. +40%
|
$94.73 | $114.59 |
Pending
|
$114.17
+20.5%
|
| Jun 01, 2026 |
MapLight Therapeutics, Inc.
MPLT
|
BUY |
$36.00
Est. +21%
|
$29.76 | $37.61 |
Target Met
|
$37.09
+24.6%
|
| May 05, 2026 |
uniQure N.V.
QURE
|
BUY |
$28.00
Est. +35%
|
$20.78 | $50.47 |
Target Met
|
$41.81
+101.2%
|
| Apr 16, 2026 |
Definium Therapeutics, Inc.
DFTX
|
BUY |
$30.00
Est. +34%
|
$22.46 | $49.20 |
Target Met
|
$44.19
+96.7%
|
| Mar 09, 2026 |
Xenon Pharmaceuticals Inc
XENE
|
BUY |
$89.00
Est. +45%
|
$61.58 | $63.95 |
Pending
|
$60.96
-1.0%
|
| Mar 02, 2026 |
uniQure N.V.
QURE
|
BUY |
$14.00
Est. +36%
|
$10.30 | $50.47 |
Target Met
|
$41.81
+305.9%
|
| Feb 26, 2026 |
Rhythm Pharmaceuticals Inc.
RYTM
|
BUY |
$131.00
Est. +32%
|
$99.54 | $114.59 |
Pending
|
$114.17
+14.7%
|
| Feb 24, 2026 |
Biomarin Pharmaceutical Inc. - Registered Shares
BMRN
|
BUY |
$68.00
Est. +11%
|
$61.44 | $66.28 |
Precision Hit (±3%)
|
$58.99
-4.0%
|
| Feb 13, 2026 |
Vertex Pharmaceuticals, Inc.
VRTX
|
BUY |
$466.00
Est. +0%
|
$465.02 | $529.08 |
Target Met
|
$528.04
+13.6%
|
| Feb 12, 2026 |
Alnylam Pharmaceuticals Inc
ALNY
|
BUY |
$444.00
Est. +42%
|
$313.05 | $345.90 |
Pending
|
$312.78
-0.1%
|
| Dec 11, 2025 |
Acadia Pharmaceuticals Inc
ACAD
|
SELL |
$25.00
Est. +7%
|
$26.81 | $19.89 (Low) |
Target Met
|
$25.97
+3.1%
|
| Oct 29, 2025 |
Neurocrine Biosciences, Inc.
NBIX
|
BUY |
$183.00
Est. +28%
|
$143.09 | $174.38 |
Pending
|
$174.26
+21.8%
|
| Oct 06, 2025 |
Alnylam Pharmaceuticals Inc
ALNY
|
BUY |
$495.00
Est. +8%
|
$456.35 | $495.55 |
Bullseye Hit (±1%)
|
$312.78
-31.5%
|
| Nov 20, 2024 |
Neurogene Inc
NGNE
|
BUY |
$46.00
Est. +200%
|
$15.33 | $37.06 |
Miss
|
$35.34
+130.5%
|
| Nov 12, 2024 |
Neurogene Inc
NGNE
|
SELL |
$60.00
Est. +7%
|
$64.48 | $6.88 (Low) |
Target Met
|
$35.34
+45.2%
|
| Nov 04, 2024 |
Alkermes plc
ALKS
|
BUY |
$36.00
Est. +35%
|
$26.59 | $36.45 |
Precision Hit (±3%)
|
$54.58
+105.3%
|
| Oct 24, 2024 |
Alkermes plc
ALKS
|
SELL |
$25.00
Est. +7%
|
$26.85 | $25.17 (Low) |
Bullseye Hit (±1%)
|
$54.58
-103.3%
|
| Aug 21, 2024 |
Biomarin Pharmaceutical Inc. - Registered Shares
BMRN
|
BUY |
$115.00
Est. +23%
|
$93.84 | $94.64 |
Miss
|
$58.99
-37.1%
|
| Aug 15, 2024 |
Vigil Neuroscience Inc
VIGL
|
BUY |
$11.00
Est. +253%
|
$3.12 | $8.10 |
Miss
|
$8.05
+158.0%
|
| Aug 06, 2024 |
Biomarin Pharmaceutical Inc. - Registered Shares
BMRN
|
BUY |
$112.00
Est. +30%
|
$85.99 | $94.85 |
Miss
|
$58.99
-31.4%
|
| Jul 02, 2024 |
Rapport Therapeutics Inc.
RAPP
|
BUY |
$35.00
Est. +38%
|
$25.44 | $29.74 |
Miss
|
$38.97
+53.2%
|
| Jun 27, 2024 |
Alnylam Pharmaceuticals Inc
ALNY
|
BUY |
$295.00
Est. +19%
|
$247.40 | $326.03 |
Target Met
|
$312.78
+26.4%
|
| Jun 27, 2024 |
Ionis Pharmaceuticals Inc
IONS
|
BUY |
$53.00
Est. +11%
|
$47.70 | $52.34 |
Precision Hit (±3%)
|
$81.80
+71.5%
|
| Jun 24, 2024 |
Alnylam Pharmaceuticals Inc
ALNY
|
BUY |
$247.00
Est. +8%
|
$227.92 | $326.03 |
Target Met
|
$312.78
+37.2%
|
| May 22, 2024 |
Biogen Inc
BIIB
|
BUY |
$275.00
Est. +22%
|
$225.21 | $237.98 |
Miss
|
$216.12
-4.0%
|
| May 20, 2024 |
Dyne Therapeutics Inc
DYN
|
BUY |
$41.00
Est. +48%
|
$27.68 | $47.45 |
Target Met
|
$23.07
-16.7%
|
| Apr 30, 2024 |
Contineum Therapeutics Inc. - Ordinary Shares - Class A
CTNM
|
BUY |
$29.00
Est. +81%
|
$16.00 | $21.92 |
Miss
|
$15.10
-5.6%
|
| Oct 10, 2023 |
Neumora Therapeutics Inc.
NMRA
|
BUY |
$26.00
Est. +138%
|
$10.91 | $15.99 |
Miss
|
$1.67
-84.7%
|
| Aug 08, 2022 |
Karuna Therapeutics Inc
KRTX
|
BUY |
$260.00
Est. +8%
|
$241.19 | - | - |
$329.83
+36.8%
|
| Jul 11, 2022 |
Vertex Pharmaceuticals, Inc.
VRTX
|
SELL |
$240.00
Est. +19%
|
$295.46 | - | - |
$528.04
-78.7%
|
| Mar 01, 2022 |
Acadia Pharmaceuticals Inc
ACAD
|
SELL |
$20.00
Est. +20%
|
$25.07 | - | - |
$25.97
-3.6%
|
| Feb 24, 2022 |
Sage Therapeutics Inc
SAGE
|
BUY |
$58.00
Est. +67%
|
$34.71 | - | - |
$8.68
-75.0%
|
| Feb 11, 2022 |
Neurocrine Biosciences, Inc.
NBIX
|
BUY |
$136.00
Est. +59%
|
$85.53 | - | - |
$174.26
+103.7%
|
Rhythm Pharmaceuticals Inc.
RYTM
Jun 15, 2026
Signal & Target
BUY
$133.00
Start Price
$94.73
Best Price (1Y)
$114.59
Current Price
$114.17
Return
+20.5%
MapLight Therapeutics, Inc.
MPLT
Jun 01, 2026
Signal & Target
BUY
$36.00
Start Price
$29.76
Best Price (1Y)
$37.61
Current Price
$37.09
Return
+24.6%
uniQure N.V.
QURE
May 05, 2026
Signal & Target
BUY
$28.00
Start Price
$20.78
Best Price (1Y)
$50.47
Current Price
$41.81
Return
+101.2%
Definium Therapeutics, Inc.
DFTX
Apr 16, 2026
Signal & Target
BUY
$30.00
Start Price
$22.46
Best Price (1Y)
$49.20
Current Price
$44.19
Return
+96.7%
Xenon Pharmaceuticals Inc
XENE
Mar 09, 2026
Signal & Target
BUY
$89.00
Start Price
$61.58
Best Price (1Y)
$63.95
Current Price
$60.96
Return
-1.0%
uniQure N.V.
QURE
Mar 02, 2026
Signal & Target
BUY
$14.00
Start Price
$10.30
Best Price (1Y)
$50.47
Current Price
$41.81
Return
+305.9%
Rhythm Pharmaceuticals Inc.
RYTM
Feb 26, 2026
Signal & Target
BUY
$131.00
Start Price
$99.54
Best Price (1Y)
$114.59
Current Price
$114.17
Return
+14.7%
Signal & Target
BUY
$68.00
Start Price
$61.44
Best Price (1Y)
$66.28
Current Price
$58.99
Return
-4.0%
Vertex Pharmaceuticals, Inc.
VRTX
Feb 13, 2026
Signal & Target
BUY
$466.00
Start Price
$465.02
Best Price (1Y)
$529.08
Current Price
$528.04
Return
+13.6%
Alnylam Pharmaceuticals Inc
ALNY
Feb 12, 2026
Signal & Target
BUY
$444.00
Start Price
$313.05
Best Price (1Y)
$345.90
Current Price
$312.78
Return
-0.1%
Acadia Pharmaceuticals Inc
ACAD
Dec 11, 2025
Signal & Target
SELL
$25.00
Start Price
$26.81
Best Price (1Y)
$19.89
Current Price
$25.97
Return
+3.1%
Neurocrine Biosciences, Inc.
NBIX
Oct 29, 2025
Signal & Target
BUY
$183.00
Start Price
$143.09
Best Price (1Y)
$174.38
Current Price
$174.26
Return
+21.8%
Alnylam Pharmaceuticals Inc
ALNY
Oct 06, 2025
Signal & Target
BUY
$495.00
Start Price
$456.35
Best Price (1Y)
$495.55
Current Price
$312.78
Return
-31.5%
Neurogene Inc
NGNE
Nov 20, 2024
Signal & Target
BUY
$46.00
Start Price
$15.33
Best Price (1Y)
$37.06
Current Price
$35.34
Return
+130.5%
Neurogene Inc
NGNE
Nov 12, 2024
Signal & Target
SELL
$60.00
Start Price
$64.48
Best Price (1Y)
$6.88
Current Price
$35.34
Return
+45.2%
Alkermes plc
ALKS
Nov 04, 2024
Signal & Target
BUY
$36.00
Start Price
$26.59
Best Price (1Y)
$36.45
Current Price
$54.58
Return
+105.3%
Alkermes plc
ALKS
Oct 24, 2024
Signal & Target
SELL
$25.00
Start Price
$26.85
Best Price (1Y)
$25.17
Current Price
$54.58
Return
-103.3%
Signal & Target
BUY
$115.00
Start Price
$93.84
Best Price (1Y)
$94.64
Current Price
$58.99
Return
-37.1%
Vigil Neuroscience Inc
VIGL
Aug 15, 2024
Signal & Target
BUY
$11.00
Start Price
$3.12
Best Price (1Y)
$8.10
Current Price
$8.05
Return
+158.0%
Signal & Target
BUY
$112.00
Start Price
$85.99
Best Price (1Y)
$94.85
Current Price
$58.99
Return
-31.4%
Rapport Therapeutics Inc.
RAPP
Jul 02, 2024
Signal & Target
BUY
$35.00
Start Price
$25.44
Best Price (1Y)
$29.74
Current Price
$38.97
Return
+53.2%
Alnylam Pharmaceuticals Inc
ALNY
Jun 27, 2024
Signal & Target
BUY
$295.00
Start Price
$247.40
Best Price (1Y)
$326.03
Current Price
$312.78
Return
+26.4%
Ionis Pharmaceuticals Inc
IONS
Jun 27, 2024
Signal & Target
BUY
$53.00
Start Price
$47.70
Best Price (1Y)
$52.34
Current Price
$81.80
Return
+71.5%
Alnylam Pharmaceuticals Inc
ALNY
Jun 24, 2024
Signal & Target
BUY
$247.00
Start Price
$227.92
Best Price (1Y)
$326.03
Current Price
$312.78
Return
+37.2%
Biogen Inc
BIIB
May 22, 2024
Signal & Target
BUY
$275.00
Start Price
$225.21
Best Price (1Y)
$237.98
Current Price
$216.12
Return
-4.0%
Dyne Therapeutics Inc
DYN
May 20, 2024
Signal & Target
BUY
$41.00
Start Price
$27.68
Best Price (1Y)
$47.45
Current Price
$23.07
Return
-16.7%
Signal & Target
BUY
$29.00
Start Price
$16.00
Best Price (1Y)
$21.92
Current Price
$15.10
Return
-5.6%
Neumora Therapeutics Inc.
NMRA
Oct 10, 2023
Signal & Target
BUY
$26.00
Start Price
$10.91
Best Price (1Y)
$15.99
Current Price
$1.67
Return
-84.7%
Karuna Therapeutics Inc
KRTX
Aug 08, 2022
Signal & Target
BUY
$260.00
Start Price
$241.19
Best Price (1Y)
-
Current Price
$329.83
Return
+36.8%
Vertex Pharmaceuticals, Inc.
VRTX
Jul 11, 2022
Signal & Target
SELL
$240.00
Start Price
$295.46
Best Price (1Y)
-
Current Price
$528.04
Return
-78.7%
Acadia Pharmaceuticals Inc
ACAD
Mar 01, 2022
Signal & Target
SELL
$20.00
Start Price
$25.07
Best Price (1Y)
-
Current Price
$25.97
Return
-3.6%
Sage Therapeutics Inc
SAGE
Feb 24, 2022
Signal & Target
BUY
$58.00
Start Price
$34.71
Best Price (1Y)
-
Current Price
$8.68
Return
-75.0%
Neurocrine Biosciences, Inc.
NBIX
Feb 11, 2022
Signal & Target
BUY
$136.00
Start Price
$85.53
Best Price (1Y)
-
Current Price
$174.26
Return
+103.7%