23andMe Holding Profit Margin

The latest profit margin for ME is -134.54% as of June 2025. That compares with -317.03% in the prior-year period — up 57.6% year over year. That is below the Healthcare sector average of 21.34%. Investors often review this figure alongside 23andMe Holding's historical trend and sector peers before judging valuation or financial health.

Over the past year, ME's profit margin moved from -317.03% to -134.54% — a 57.6% year-over-year increase. If the trend continues in the same direction for several quarters, it can signal a meaningful shift in 23andMe Holding's valuation or profitability profile.

Against Healthcare companies, ME currently prints -134.54% for profit margin, while the sector average sits near 21.34%. That is roughly 730.6% below the sector mean. Large gaps often invite a closer look at 23andMe Holding's growth, margins, and balance sheet.

Profit Margin shows how effectively 23andMe Holding converts resources into returns. At -134.54%, ME may look efficient or underperforming depending on peer benchmarks and trend direction. That compares with -317.03% in the prior-year period — up 57.6% year over year. Pair the percentage with revenue growth and leverage for a fuller health check.

After noting ME's profit margin (-134.54%), review year-over-year change from -317.03%, peer averages, and a few neighboring metrics such as revenue, margins, or valuation multiples. That combination usually beats staring at a single figure. The navigation links on this page jump you to those related views.