Ionis Pharmaceuticals Profit Margin

Ionis Pharmaceuticals (IONS) currently reports a profit margin of -18.86% as of June 2026. That compares with -0.35% in the prior-year period — down 5344.9% year over year. That is below the Healthcare sector average of 13.76%. Use the charts on this page to explore Ionis Pharmaceuticals's profit margin history and peer comparisons.

Ionis Pharmaceuticals's profit margin decreased from -0.35% to -18.86% — a 5344.9% year-over-year decrease (period ending June 2026). Watching multi-year history on the chart below helps separate one-off swings from a lasting trend.

Ionis Pharmaceuticals's profit margin of -18.86% is lower than the Healthcare sector average of 13.76%. That is roughly 237.1% below the sector mean. A reading lower peers can reflect different growth expectations, capital structure, or profitability — so it is worth checking the peer comparison chart before drawing conclusions.

There is no universal 'good' profit margin, but Ionis Pharmaceuticals's current -18.86% should be judged against Healthcare norms (sector average: 13.76%) and against IONS's own history. Strong, stable readings often indicate durable competitive advantage; volatile or declining ones deserve a closer look at margins and capital efficiency.

Start with the current profit margin of -18.86%, then check the historical chart for trend and the peer comparison chart for relative positioning. The Healthcare average is 13.76%. From there, open related valuation or income-statement pages for Ionis Pharmaceuticals, and consider following IONS for alerts when major investors trade the stock.