Illumina Profit Margin

The latest profit margin for ILMN is 18.36% as of June 2026. That compares with 29.37% in the prior-year period — down 37.5% year over year. That is above the Healthcare sector average of 13.89%. Investors often review this figure alongside Illumina's historical trend and sector peers before judging valuation or financial health.

Over the past year, ILMN's profit margin moved from 29.37% to 18.36% — a 37.5% year-over-year decrease. If the trend continues in the same direction for several quarters, it can signal a meaningful shift in Illumina's valuation or profitability profile.

Against Healthcare companies, ILMN currently prints 18.36% for profit margin, while the sector average sits near 13.89%. That is roughly 32.2% above the sector mean. Large gaps often invite a closer look at Illumina's growth, margins, and balance sheet.

Profit Margin shows how effectively Illumina converts resources into returns. At 18.36%, ILMN may look efficient or underperforming depending on peer benchmarks and trend direction. That compares with 29.37% in the prior-year period — down 37.5% year over year. Pair the percentage with revenue growth and leverage for a fuller health check.

After noting ILMN's profit margin (18.36%), review year-over-year change from 29.37%, peer averages, and a few neighboring metrics such as revenue, margins, or valuation multiples. That combination usually beats staring at a single figure. The navigation links on this page jump you to those related views.