Exact Sciences Profit Margin

The latest profit margin for EXAS is -6.4% as of December 2025. That compares with -37.29% in the prior-year period — up 82.8% year over year. That is below the Healthcare sector average of 13.89%. Investors often review this figure alongside Exact Sciences's historical trend and sector peers before judging valuation or financial health.

Over the past year, EXAS's profit margin moved from -37.29% to -6.4% — a 82.8% year-over-year increase. If the trend continues in the same direction for several quarters, it can signal a meaningful shift in Exact Sciences's valuation or profitability profile.

Against Healthcare companies, EXAS currently prints -6.4% for profit margin, while the sector average sits near 13.89%. That is roughly 146.1% below the sector mean. Large gaps often invite a closer look at Exact Sciences's growth, margins, and balance sheet.

Profit Margin shows how effectively Exact Sciences converts resources into returns. At -6.4%, EXAS may look efficient or underperforming depending on peer benchmarks and trend direction. That compares with -37.29% in the prior-year period — up 82.8% year over year. Pair the percentage with revenue growth and leverage for a fuller health check.

After noting EXAS's profit margin (-6.4%), review year-over-year change from -37.29%, peer averages, and a few neighboring metrics such as revenue, margins, or valuation multiples. That combination usually beats staring at a single figure. The navigation links on this page jump you to those related views.