AstraZeneca PLC Profit Margin

As of the most recent data (December 2025), AZNCF shows a profit margin of 17.53%. That compares with 13.02% in the prior-year period — up 34.6% year over year. That is above the Healthcare sector average of 15.29%. Scroll down for historical charts and peer comparison views.

Compared with the year-ago period, AZNCF's profit margin is now 17.53% (was 13.02%) — a 34.6% year-over-year increase. Pairing that YoY change with peer averages gives a clearer picture of whether AstraZeneca PLC is outperforming or lagging.

The Healthcare sector average profit margin is about 15.29%. AstraZeneca PLC is at 17.53%, which is higher that average. That is roughly 14.7% above the sector mean. Use the comparison chart on this page to see how AZNCF stacks up against individual peers as well.

That compares with 13.02% in the prior-year period — up 34.6% year over year. Improvement over multiple periods is generally more meaningful than a single strong quarter. Compare AstraZeneca PLC with peers to see if the move is company-specific or sector-wide.

Besides this profit margin page, Stockcircle has AstraZeneca PLC's full stock overview, other financial metrics, insider and congress trade tabs, and tools to follow the stock. Together they help you connect profit margin (currently 17.53%) with ownership activity and broader fundamentals.