Astrazeneca plc - ADR

Astrazeneca plc - ADR

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Market Cap$294.4B
Close$

Compare to Similar Companies

P/E RatioDividendsReturn on EquityPrice-to-SalesDebt-to-Equity
Astrazeneca plc - ADRAstrazeneca plc - ADR27.51.71%21%4.80.6

Earnings Call Q1 2026

April 29, 2026 - AI Summary

Q1 performance: solid growth and profit momentum - Total revenue +8% YoY (reported; also framed as strong growth across key regions/therapy areas). - Core operating profit +12% (operating leverage focus). - Core EPS +5% to $2.58; growth “held back” by a lower tax rate in Q1 2025 (so underlying operating strength better than EPS headline alone). - Core gross margin: 83%; company continues to expect stable to slightly higher core gross margin vs 2025.
Financial outlook/guidance reiterated (forecasts) - Reiterated full-year guidance: - Total revenue: mid- to high single-digit growth (CER implied). - Core EPS: low double-digit growth at constant exchange rates (CER). - FX expectation: low single-digit positive FX impact on total revenue (based on average March rates) and neutral FX impact on core EPS. - Anticipated capex increase ~1/3 in 2026 (includes announced multiyear manufacturing investments).
R&D & pipeline execution: multiple “high-value” readouts and catalyst-heavy 2026 - Company reported 4 positive Phase III readouts recently (including 2 NMEs: tozorakimab and efzimfotase alfa). - Oncology/Imfinzi franchise momentum: - EMERALD-3: STRIDE regimen in earlier local/regional HCC showed statistically significant PFS improvement for STRIDE + lenvatinib; OS positive trend; additional data follow-up; expected at ASCO. - Additional Imfinzi readout cadence: VOLGA (genitourinary), and AVANZAR + PACIFIC-9 later in 2026. - ADC & other oncology pipeline set up future trial expansion and ASCO updates (e.g., puxi-sam, folate receptor alpha ADC plans; sone-ve data support CLARITY-Gastric01).

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$391.26

Current Fair Value

122% upside

Undervalued by 122% based on the discounted cash flow analysis.

Share Statistics

Market cap$294.40 Billion
Enterprise Value$319.39 Billion
Dividend Yield$3.20 (1.71%)
Earnings per Share$6.6
Beta0.22
Outstanding Shares1,549,000,000

Return

Return on Equity21.16%ROE
Return on Assets9.03%
Return on Invested Capital16.80%

Valuation & Multiples

P/E Ratio27.52P/E Ratio
PEG49.97PEG
Price to Sales4.76Price to Sales
Price to Book Ratio5.69Price to Book Ratio
Enterprise Value to Revenue5.44
Enterprise Value to EBIT22.78
Enterprise Value to Net Income31
Total Debt to Enterprise0.1
Debt to Equity0.63Debt to Equity

Revenue Sources

No data

Insider Trades

Last Earnings Call

Report Date
May 5, 2026
EPS Estimate
$2.53
Average shareholder expectation
Revenue Estimate
$14.90 B
Average shareholder expectation

Next Earnings Call

Expected Date
July 27, 2026
EPS Estimate
$2.53
Average shareholder expectation
Revenue Estimate
$15.47 B
Average shareholder expectation

Institutional Put/Call Ratio

Market sentiment based on institutional option activity.

Put/Call Ratio0.9628 27.02%
Total Calls3,479,401 35.47%
Total Puts3,350,045 10.29%

Institutional Ownership

Holdings and activity of institutional investors.

Ownership %96.56% 64.96%
Total Invested$149.90B 232.68%
Investors Holding1,354 45.00%

ESG Score

No data

About AstraZeneca Plc

CEO: Pascal Soriot

AstraZeneca Plc is a holding company, which engages in the research, development, and manufacture of pharmaceutical products. Its pipeline are used for the following therapy areas: oncology, cardiovascular, renal, metabolism, and respira...

Relevant Senate Committees

Finance

This is a critically important committee for AstraZeneca. It controls taxation (corporate tax rates, R&D credits), trade policy (affecting global supply chains and market access), and entitlement spending (Medicare/Medicaid drug pricing and reimbursement), all directly impacting profitability and revenue.

Appropriations

This committee allocates federal discretionary spending, directly impacting funding for biomedical research (e.g., NIH) and government healthcare programs that purchase pharmaceutical products, thereby affecting AstraZeneca's potential research collaborations and market opportunities.

Health, Education, Labor, and Pensions

This committee directly regulates the FDA (drug approval, safety, marketing) and NIH (research funding), making it central to AstraZeneca's product development, regulatory pathways, and market access. It profoundly impacts the pharmaceutical and biotech sectors.

Judiciary

This committee's oversight of antitrust laws directly impacts potential mergers and acquisitions, and its role in intellectual property protection (patents) is critical for pharmaceutical companies like AstraZeneca, which rely heavily on proprietary research and development.