Jim Simons's position in United Therapeutics is currently worth $512 Million. That's 0.68% of their equity portfolio (20th largest holding). The investor owns 6.23% of the outstanding United Therapeutics stock. The first United Therapeutics trade was made in Q2 2013. Since then Jim Simons bought shares twenty more times and sold shares on fifteen occasions. The stake costed the investor $314 Million, netting the investor a gain of 63% so far.