Jim Simons's position in Regeneron Pharmaceuticals is currently worth $234 Million. That's 0.34% of their equity portfolio (49th largest holding). The first Regeneron Pharmaceuticals trade was made in Q2 2013. Since then Jim Simons bought shares twenty more times and sold shares on 21 occasions. The stake costed the investor $163 Million, netting the investor a gain of 44% so far.