Jim Simons acquired 10 Million Glaxosmithkline plc - ADR shares worth $444 Million. That's 0.59% of their equity portfolio (25th largest holding). The first Glaxosmithkline plc - ADR trade was made in Q2 2013. Since then Jim Simons bought shares 24 more times and sold shares on eleven occasions. The stake costed the investor $442 Million, netting the investor a gain of 0.5% so far.