Jim Simons's position in Astrazeneca plc is currently worth $20.9 Million. That's 0.03% of their equity portfolio (622nd largest holding). The first Astrazeneca plc trade was made in Q2 2013. Since then Jim Simons bought shares twenty more times and sold shares on 27 occasions. The stake costed the investor $16.4 Million, netting the investor a gain of 28% so far.