Jim Simons acquired 6.46M Alkermes plc shares worth $296M. That's 0.40% of their equity portfolio (35th largest holding). The investor owns 3.90% of the outstanding Alkermes plc stock. The first Alkermes plc trade was made in Q2 2013. Since then Jim Simons bought shares 26 more times and sold shares on twenty occasions. The stake costed the investor $175M, netting the investor a gain of 70% so far.