Jim Simons acquired 1.22 Million Abbvie shares worth $226 Million. That's 0.33% of their equity portfolio (46th largest holding). The first Abbvie trade was made in Q2 2013. Since then Jim Simons bought shares 23 more times and sold shares on 24 occasions. The stake costed the investor $114 Million, netting the investor a gain of 99% so far.