George Soros's position in Astrazeneca plc is currently worth $183 Million. It makes up 6.08% of their stock portfolio and is their biggest holding. The first Astrazeneca plc trade was made in Q2 2014. Since then George Soros bought shares three more times and sold shares on one occasions. The investor's estimated purchase price is $197 Million, resulting in a loss of 7.0%.