George Soros's position in Astrazeneca plc is currently worth $213 Million. It makes up 6.69% of their stock portfolio and is their biggest holding. The first Astrazeneca plc trade was made in Q2 2014. Since then George Soros bought shares four more times and sold shares on one occasions. The investor's estimated purchase price is $232 Million, resulting in a loss of 8.2%.