Cathie Wood acquired 6.17 Million Ionis Pharmaceuticals shares worth $244 Million. That's 1.54% of their equity portfolio (21st largest holding). The investor owns 4.39% of the outstanding Ionis Pharmaceuticals stock. The first Ionis Pharmaceuticals trade was made in Q4 2016. Since then Cathie Wood bought shares twelve more times and sold shares on seven occasions. The investor's estimated purchase price is $293 Million, resulting in a loss of 17%.