Illumina Inc

Illumina Inc

ILMN

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Market Cap$24.66B
Close$

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P/E RatioDividendsReturn on EquityPrice-to-SalesDebt-to-Equity
Illumina IncIllumina Inc29.2-28%6.11

Earnings Call Q1 2026

April 30, 2026 - AI Summary

Strong Q1 Performance: Illumina reported Q1 2026 revenue of $1.09 billion, exceeding guidance by $20 million, driven by better-than-expected instrument sales and clinical consumable sales. This reflects a 4.8% year-over-year increase and an organic growth of 1.2%. Non-GAAP EPS was $1.15, approximately 19% growth YOY, signaling strong operational performance despite a higher cost environment.
Raised Full-Year Guidance: The company has updated its revenue guidance upwards by $20 million to a range of $4.52 billion to $4.62 billion, reflecting Q1 outperformance. Operating margins are projected between 23.4% to 23.6%. This guidance indicates confidence in the growth of clinical markets, which continue to experience strong demand.
Clinical Market Momentum: Clinical sequencing consumables grew 20% year-over-year (excluding China), demonstrating robust adoption of sequencing-based diagnostics and data-intensive applications. Clinical markets accounted for over 65% of sequencing consumables revenue, suggesting a strong demand that could lead to sustained growth.

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$147.38

Target Price by Analysts

13.8% downsideIllumina Target Price DetailsTarget Price
$95.67

Current Fair Value

44% downside

Overvalued by 44% based on the discounted cash flow analysis.

Share Statistics

Market cap$24.66 Billion
Enterprise Value$26.51 Billion
Dividend Yield$- (-)
Earnings per Share$5.48
Beta1.42
Outstanding Shares153,000,000

Return

Return on Equity28.17%ROE
Return on Assets13.01%
Return on Invested Capital19.43%

Valuation & Multiples

P/E Ratio29.23P/E Ratio
PEG1276.36PEG
Price to Sales6.1Price to Sales
Price to Book Ratio9.0Price to Book Ratio
Enterprise Value to Revenue6.03
Enterprise Value to EBIT27.33
Enterprise Value to Net Income31
Total Debt to Enterprise0.11
Debt to Equity0.97Debt to Equity

Revenue Sources

No data

Insider Trades

Last Earnings Call

Report Date
May 14, 2026
EPS Estimate
$1.06
Average shareholder expectation
Revenue Estimate
$1.07 B
Average shareholder expectation

Next Earnings Call

Expected Date
July 30, 2026
EPS Estimate
$1.24
Average shareholder expectation
Revenue Estimate
$1.13 B
Average shareholder expectation

Institutional Put/Call Ratio

Market sentiment based on institutional option activity.

Put/Call Ratio0.5648 25.86%
Total Calls745,420 73.74%
Total Puts421,024 51.56%

Institutional Ownership

Holdings and activity of institutional investors.

Ownership %101.86% 0.46%
Total Invested$19.20B 7.51%
Investors Holding868 29.00%

ESG Score

No data

About Illumina Inc

CEO: Francis deSouza

Relevant Senate Committees

Joint Committee on Taxation

Assists tax-writing committees with legislation and provides revenue estimates. Its expertise and analysis directly influence the design and scoring of tax laws, including corporate tax structures and R&D credits, which significantly impact Illumina's financial performance and investment decisions.

Finance

Controls taxation, trade, and entitlement spending. Tax policy significantly impacts corporate profitability. Crucially, this committee influences Medicare pricing and reimbursement policies for genomic tests, which is a key factor for market adoption and revenue in the clinical genomics space.

Appropriations

Allocates discretionary federal spending. Its subcommittees directly determine the precise funding for scientific research (e.g., NIH, CDC) and healthcare programs, which translates into direct revenue streams for Illumina's customers and influences their purchasing power for instruments.

Health, Education, Labor, and Pensions

Regulates the FDA and NIH. NIH funding is a major driver for Illumina's customer base (research institutions). FDA oversight of diagnostic applications of Illumina's instruments, and general regulation of the biotech/pharmaceutical sectors, directly impacts the company's market and product approvals.

Judiciary

Oversees antitrust laws and intellectual property. Illumina, as a dominant player in its market with significant IP, is directly impacted by patent protection and potential antitrust reviews (e.g., regarding M&A activities like the GRAIL acquisition).

Special Committee on Aging

Investigates issues affecting older Americans. Genomics is fundamental to understanding and diagnosing age-related diseases. While advisory, its hearings and policy recommendations can significantly influence research funding and public health initiatives related to aging, impacting demand for Illumina's technologies.

Armed Services

Oversees the Department of Defense and authorizes the annual NDAA. Genomics technology is crucial for military applications such as biodefense, soldier health, and forensics, directly influencing R&D funding and procurement for emerging military technologies relevant to Illumina.

Veterans' Affairs

Oversees the Department of Veterans Affairs. Funding decisions directly impact government healthcare contractors and medical device manufacturers. Illumina's genomic instruments are increasingly vital for personalized medicine and diagnostics in VA hospitals.

Select Committee on Intelligence

Members receive classified briefings on global threats. Genomics technology (Illumina's core) has critical applications in biodefense, biosecurity, and intelligence, creating potential for non-public information regarding strategic priorities and funding for such technologies.