Tweedy Browne acquired 2.98 Million Ionis Pharmaceuticals shares worth $100 Million. That's 9.04% of their entire equity portfolio (5th largest holding). The investor owns 1.87% of the outstanding Ionis Pharmaceuticals stock. The first Ionis Pharmaceuticals trade was made in Q1 2022. Since then Tweedy Browne bought shares one more times and sold shares on eight occasions. The investor's estimated purchase price is $104 Million, resulting in a loss of 3.6%.