Jim Simons's position in Regeneron Pharmaceuticals is currently worth $173 Million. That's 0.29% of their equity portfolio (56th largest holding). The first Regeneron Pharmaceuticals trade was made in Q2 2013. Since then Jim Simons bought shares twenty more times and sold shares on 22 occasions. The stake costed the investor $111 Million, netting the investor a gain of 56% so far.